What is Transfer Factor?
Is it a vitamin, mineral or herb?
• Where are Transfer Factors found?
• What are Transfer Factors and how do they work?
• What role do Transfer Factors play in the immune system?
• Are Transfer Factors made of sugars, proteins or fats?
• How was Transfer Factor discovered?
• What is colostrum?
• Quality Control Protocol: Herd Management
• Relieving Concerns about the «Mad Cow Disease» By Richard H. Bennett, Ph.D.
• Is Transfer Factor™ FDA approved?
• Is Transfer Factor approved by the USDA?
Can anyone take Transfer Factor?
• Can it be taken with any other vitamins, ginseng or any other nutritional product?
• Is Transfer Factor™ safe?
• I have heard reports of people exceeding the recommended serving size of Transfer Factor. Is this safe?
• Is it safe to take multiple capsules of Transfer Factor™ a day?
• Can a person use more than the recommended serving size of Transfer Factor Plus™?
• Is there a toxic level of Transfer Factors?
• Any fear of overdose?
• Do Health Professionals work with Transfer Factor?
• Does any of the 4Life TF products contain IGF-1?
Are there studies to back up the power of Transfer Factors?
• Has Transfer Factor™ been scientifically validated?
• What prompted these scientists to look for Transfer Factor in colostrum?
Transfer Factor™ is isolated from colostrum, what about milk allergies and lactose intolerance?
• Can persons who have milk allergies use Transfer Factor XF?
• Can persons who are lactose intolerant use Transfer Factor XF?
• Can someone be allergic to Transfer Factors?
• Is Transfer Factor™ only good for newborns?
• Is transfer factor safe for infants?
• Who can benefit from taking Transfer Factor XF?
• Can pregnant women take Transfer Factor XF?
• Why should I use Transfer Factor XF if I received immune information as an infant?
• Why consume TF when you are well?
• How often should I take Transfer Factor XF?
• Do you advise daily use? How long will the immunity last?
• If the immunity lasts for four weeks, why should you continue to consume more?
• Can I still get sick when I am consuming TF?
• Do stomach acids or other functions of the digestive tract neutralize Transfer Factors?
• What conditions are responsive to Transfer Factor™?
• Are there any reports about Transfer Factor™ helping people with cancer?
• What about colds?
• What diseases are Transfer Factors used for?
• But what about antibiotics?
Is it expensive?
• Is Transfer Factor protected by Patent?
• What is the difference between Transfer Factors and antibodies?
• Are there any differences between dried colostrum and 4Life’s Transfer Factor XF?
• How does Transfer Factor™ compare to the colostrum products that are on the market now?
• How does ingesting Transfer Factors orally compare to injecting Transfer Factors from blood preparations?
• Is blood the only source of Transfer Factor?
• Who makes Transfer Factor?
• Is there a limit to how hot the product can get?
• Is the Transfer Factor molecule heat sensitive? What about increased temperatures in shipping of the product to the customer?
• If Transfer Factor™ is so effective why hasn’t the pharmaceutical industry jumped on Transfer Factor™?
• Are there reasons why we haven’t seen Transfer Factor as a food supplement before now?
• How does one discuss Transfer Factor™ in terms of structure-function claims?
Is it a vitamin, mineral or herb? No. It is a supplement unlike any other. It is in a class of it’s own.
Where are Transfer Factors found? In the blood and in the first milk after a mother gives birth.
What role do Transfer Factors play in the immune system? These are an inducer fraction, a antigen specific fraction and a suppressor fraction.¹ The immune system must be able to respond quickly, respond specifically and not exhaust itself by over responding and attacking normal tissue. The three transfer factor fractions were named because of the discovered affects they had on immune system. The inducer fraction triggers a general state of readiness in the immune system. The antigen specific fraction is an array of critical tags used by the immune system to identify a host of enemy microbes. The suppressor fraction is as important as the other fractions in that the components of this fraction keep the immune system from focusing all its strength on a defeated infection while ignoring new microbial threats. The suppressor fraction is also responsible for controlling allergic reactions and blocking autoimmune disorders.
Are Transfer Factors made of sugars, proteins or fats? Isolated transfer factors have been determined to be a chain of small peptides consisting of 44 amino acids. Amino acids are the building blocks of proteins.
What are Transfer Factors and how do they work? Soon after giving birth, female mammals produce colostrum, which is a milk-like substance that jump-starts a newborn’s immune system. Researchers now believe that the benefits of colostrum don’t necessarily end there. If you have a compromised immune system or are just looking for a boost to your healthy immune system. Transfer Factor is a set of messaging molecules that convey immune information within an individual’s immune system. Nature also uses transfer factor to carry immune information from one individual’s immune system to another individual. This in fact is how it got its name: by being the factor that transferred immunity from one person to another. Transfer factors are the primary communications used by the immune system to defend against harmful microbial threats. Transfer factors are small molecules that occur naturally in all mammals and are passed from mother to newborn through the mother’s first milk called colostrum. By transferring information from cell to cell, transfer factors serve as «teachers» to the cells, ensuring a strong immune system capable of surviving, even thriving, in its new environment.
How was Transfer Factor discovered? In 1949 Dr. H. Sherwood Lawrence was working on the problem of tuberculosis. What he was trying to discover was if any component of the blood could convey a tubercular sensitivity from an exposed recovered donor to a naive recipient. Whole blood transfusions could be used but only between people of the same blood type. Lawrence first separated the blood’s immune cells, the lymphocytes or white blood cells, from the whole blood. Then he broke open the lymphocytes and separated the contents of the cells into various size fractions. What he found was that a fraction of small molecules was able to transfer tuberculin sensitivity to a naive recipient. This is what Dr. Lawrence called transfer factor.
Is blood the only source of Transfer Factor? Originally it was. It was not until the mid 1980’s that two researchers came up with the idea that Transfer Factor may also be present in colostrum. The confirmation of this discovery was awarded a patent in 1989. Colostrum is now the best source of Transfer Factor.
What is colostrum? It is the first milk that a mother produces immediately after giving birth.
What prompted these scientists to look for Transfer Factor in colostrum? Those who have worked with cattle know that if a calf is not allowed to nurse from its mother it will most often die within a short time. The calves would die in spite of an abundance of food. Death in these cases was cause by infections brought on by the most common organisms. For whatever reason the immune systems of these calves were not working. Seeing this suggests that there is some kind of immune information was being transferred from the mother and her infant. The logical question then became: was it transfer factor? The answer was a resounding YES!
Transfer Factor™ is isolated from colostrum, what about milk allergies and lactose intolerance? Milk allergies are caused by the large milk proteins, primarily casein, and to a lesser extent the immunoglobulins. These proteins are completely removed from the transfer factor. Lactose intolerance is most common in Oriental populations; much less so in those of European or African decent. We are conscience of this concern and remove the lactose from our product.
Can persons who have milk allergies use Transfer Factor XF?
Yes. Transfer factors themselves are non-allergenic. Common allergens such as immunoglobulins and casein are removed from Transfer Factor products.
Can persons who are lactose intolerant use Transfer Factor XF?
Yes! Lactose intolerant persons can consume up to three grams of lactose without difficulty due to colonic bacterial digestion. The amount of residual lactose is well below these sensitivity limits.
Can someone be allergic to Transfer Factors?
Unlike antibodies that are large molecules, transfer factors are quite small.4,5 There small size makes them nonallergenic.6,7
Is Transfer Factor protected by Patent? Yes. US Patent 4,816,563 covers the molecular extraction of Transfer Factor from colostrum. 4Life Research holds the license for that patent and the Trademark for the name Transfer Factor.
Is it expensive?
Compared to any other immune boosting and modulating product on the market, Transfer Factor is extremely cost effective. The 4Life Transfer Factor products are the «Rolls Royce» of the industry. You may be able to buy cheaper but you’ll find that effectiveness wins every time. When it comes to your family’s health, what’s more important? Cheap or something that can really work?
What is the difference between Transfer Factors and antibodies?
Unlike antibodies that are large proteins, Transfer Factors are small peptides containing about eight amino acids. The small size of the transfer factors makes them non-allergenic. Antibodies are consumed by directly attaching themselves to the offending cell or protein. Transfer Factors perform a different role. Transfer factors are immune messenger molecules that educate and alert naive immune cells to an impending danger. In this regard Transfer Factors perform a catalytic role in the immune system, triggering the affect without themselves being consumed.
Are there any differences between dried colostrum and 4Life’s Transfer Factor XF?
Unlike colostrum, Transfer Factor XF contains a concentrated amount of transfer factors, the active ingredient found in colostrum. Colostrum contains bovine specific antibodies that can cause allergic reactions. However, transfer factors are not species-specific and can be given to another mammal without reaction. In addition, transfer factor supplements are vastly more concentrated than colostrum alone. In fact, you would have to consume many quarts of colostrum to receive the same benefits of one transfer factor capsule. Through a special patented process licensed to 4Life, transfer factors are separated from other components found in this “first milk.” Transfer factors readily survive digestion and are easily absorbed. In addition, Transfer Factor XF has undergone a special stabilization process to protect the effectiveness of the transfer factors.
How does Transfer Factor™ compare to the colostrum products that are on the market now?
We looked seriously at hyper immunized colostrum and eggs. These products are good but certain issues must be addressed. First the milk allergy and lactose intolerance issues as we discussed above. Second the issue of immunoglobulin or antibody effectiveness. The use of cross species antibody therapy can be effective in the short run. Long-term use is ineffective since the recipient develops antibodies to the foreign antibody thus destroying its effectiveness. Antibody therapy is given intravenously since oral consumption leads to acid degradation in the stomach.
How does ingesting Transfer Factors orally compare to injecting transfer factors from blood preparations?
Generally, the effects are very similar no matter how transfer factors enter the body. Because Transfer Factors originate in the blood, the source of Transfer Factors is identical whether they re-enter the body in concentrated form such as 4Life™ Transfer Factor™, or by injection.
Is Transfer Factor™ only good for newborns? Transfer Factor is good for everyone who needs an extra immune boost. The three groups who are most in need of immune strengthening are the young, the old, and anyone under stress. Almost all of us fall into one of these categories. We often talk of the baby-boom generation. Most of these people are at an age where already their immune systems are becoming lax. Transfer Factor is a way to boost a lagging immune system.
Is transfer factor safe for infants? Colostral transfer factor was designed by Nature for newborns. Removal of the milk allergens and lactose leaves only the essence of the immunological information in the form of Transfer Factor™.
Are there studies to back up the power of Transfer Factors? There have been over 3000 medical studies completed and 40 million dollars spent in researching the benefits of transfer factors. 4Life Transfer Factor™ and Transfer Factor Plus™ were tested for their ability to increase Natural Killer Cell (NK) activity by the Institute of Longevity Medicine in California. Natural Killer Cells seek and destroy harmful cells through direct contact. Natural Killer Cells are especially important in strengthening and supporting the immune system. Test results showed that 4Life Transfer Factor™ boosted NK cell activity 103% above normal immune response without supplementation, more than two times higher than the next highest product. The study also showed that Transfer Factor Plus™ increased the NK cell activity over 430% above normal immune response without supplementation, or about five times higher than any of the other previously tested products. With the ability of transfer factors to boost the immune system this will help stop the overuse of antibiotics. According to David Markowitz, M.D. who has been running a clinical trial in his pediatric practice, «In an aged match review of transfer factor users we have seen 74% less reported illness and 84% less use of antibiotics.»
Has Transfer Factor™ been scientifically validated? In the 50 years since Dr. Lawrence’s pioneering work, 11 international conferences have been convened and an estimated $40 million has been spent on scientific research, resulting in over 3,000 scientific papers documenting the results.
The Germ Survival Guide recommends Transfer Factor and and Transfer Factor Plus. This new book written by Kenneth A. Bock, M.D., Steven J. Bock, M.D. is designed to give families and individuals preventative strategies to use to protect against germs and environmental threats. Transfer Factor and Transfer Factor Plus are extolled in the book as an effective way to optimize immune system function so that personal immunity is at its best in the face of a variety of health threats.
Who can benefit from taking Transfer Factor XF?
Everyone who needs an extra immune boost can benefit from taking Transfer Factor XF.
Can pregnant women take Transfer Factor XF?
There have been no adverse responses reported while taking Transfer Factor XF during pregnancy, but as with any supplement, consult a physician.
Why should I use Transfer Factor XF if I received immune information as an infant?
The transfer factors we received from our mothers as infants helped educate and strengthen our naïve immune systems for the challenges of that time. Today, more than ever, we are exposed to new immune challenges, while our immune systems have become weakened with age. Strengthening our immune systems can be critical to lifelong health.
Why consume TF when you are well?
The wide benefits of transfer factors are still being explored. A healthy immune system is crucial to your overall health, cell cleansing, and cell rejuvenation. Within our bodies, there is a continuous battle between the «good» and «bad» bacteria. Giving your immune system a break can actually allow your body to direct its energies elsewhere.
How often should I take Transfer Factor XF?
Every day our bodies create new immune cells that need instruction. To meet this need, Transfer Factor XF should be used on a daily basis to provide the immune system with continual support against an environment filled with new and emerging health challenges. Transfer Factor XF, taken on a daily basis, provides effective support for the immune system.
Do you advise daily use? How long will the immunity last?
Yes. The Transfer Factor works best when taken daily. The volume of TF in your blood affects its effectiveness. If you discontinue use, your immune system will miss out on its daily support. The immunity received from Transfer Factor™ is short-term. When a germ enters your body or you are vaccinated, a deep survival mechanism is triggered within your immune system. The memory of the illness is stored through a different pathway to the transfer factors within your body. Experienced knowledge, exchanged from transfer factor to transfer factor, is not as long- lasting. Once the consumed transfer factor is washed from your body, within four to six weeks the immunity is lost. The information is transferred to your own transfer factor, but that transfer factor will eventually die, and the information is diluted down through a few generations.
If the immunity lasts for four weeks, why should you continue to consume more? (back) The volume of TF in your body is important. Every area of your body is vulnerable to attack from germs. The transfer factor must come in contact with the germ to recognize it. The more TF you have policing the body, the greater the chance that germs will be spotted early in the race for victory.
Can I still get sick when I am consuming TF?
The volume of TF in your body is important. Every area of your body is vulnerable to attack from germs. The transfer factor must come in contact with the germ to recognize it. The more TF you have policing the body, the greater the chance that germs will be spotted early in the race for victory.
Do stomach acids or other functions of the digestive tract neutralize Transfer Factors? Stomach acid or digestive enzymes do not degrade the potency of transfer factor.
If Transfer Factor™ is so effective why hasn’t the pharmaceutical industry jumped on Transfer Factor™? I think that is exactly what we are seeing in many foreign countries notably China, Czechoslovakia, Germany, Hungary, Poland, and Japan. In the US transfer factor has had an interesting history. The idea of Transfer Factor flies in the face of conventional immunology. In the 50’s antibiotics were the golden child of medicine followed in the 60’s by steroids like cortisone for inflammation and the synthetic steroid hormones like ethinyl estrogen and progestin that were used to create the birth control pill. After an initial delay Transfer Factor hit its heyday in the 70’s and early 80’s. Results however were inconsistent as researchers dove in sometimes with more enthusiasm than skill. The key feature that was missing in these investigations was a dependable assay technique for quality control of the product. The quality control issue was not resolved until the mid 1980’s. Given that transfer factor is not a single entity, the pharmaceutical companies had fits to trying to purify the material without losing efficacy. This force-fit into the single-entity, single-function drug dogma was disastrous. The next issue that slowed Transfer Factor research is the age-old issue of funding. When AIDS hit the popular press politicians shifted funding into AIDS research but with the focus on finding the cause and then finding a drug that would cure AIDS.
Are there reasons why we haven’t seen Transfer Factor as a food supplement before now? Yes, there are two doors that recently have opened that allow transfer factor to be effectively marketed now. The first door to open was the passage of DSHEA in 1994. The provision for structure-functions claims allows the story of transfer factor to be told without jeopardizing its status as a nutritional supplement. The second is technical. Transfer factor was definitely an idea way ahead of its time and it had to wait for technology to catch up. The processing methods that allow for large-scale extraction of transfer factor have only recently been perfected and a commercial product has only been available for the past year.
How does one discuss Transfer Factor™ in terms of structure-function claims? Simplistically, Transfer Factor strengthens the immune system. But that is simplistic and could be used to describe a number of herbal products and other supplements. Let me answer the question by first reiterating that transfer factor is not just a single entity. Transfer Factor is in fact a complex mixture containing three separate fractions. These three fractions are an INDUCER fraction, and ANTIGEN SPECIFIC fraction, and a SUPPRESSOR fraction. Since our immune systems fight the microbe wars for us, let me use a military analogy to explain these three functions. The inducer fraction serves as the drill Sargent of basic training whipping the immune system into shape but not telling them who to go out and attack. The antigen specific fraction is like a set of wanted posters identifying critical features of the bad guys. If we were microbes these specific identifiers would be our fingerprints, mug shots, etc. Similarly a whole set of transfer factors are made against a single microbe type. Finally the suppressor fraction is like the politicians who declare an end to the war and demobilize the troops. Without this action a lot of excessive damage is done both in war and within ourselves. When our immune system does not demobilize or overreacts we suffer from autoimmune diseases such as multiple sclerosis and allergies. Unlike most immune supplements, that provide the building blocks for proper immune function, transfer factor is immune intelligence. It is immune information and education that focuses the immune system keeping it on task and effective. This is a whole new concept in immune system strengthening.
Quality Control Transfer Factors are obtained through a proprietary, patented microfiltration process. The colostrum is collected within the first 24-48 hours of calving, then passed through the microfiltration machinery. The collection of transfer factors is from the excess colostrums, after a portion is given to the calf to protect it. That material is essentially free of all hormone additives. It is the cleanest time to collect milk for consumption and in this case, colostrum for providing transfer factors. The resultant filtrate is then pasteurized a second time and spray-dried into a fine powder. The powder then undergoes microbial testing for safety and a biological assay to ensure consistency and potency.A similar process is used on the egg yolks after they are separated from the whites. The Patent numbers are 4,816,563 and 6,468,534
Both chickens and cows live mainly outside, where they eat off the ground, drink from shared water sources, endure varying weather conditions and contend with the challenges of communal living. This leaves them exposed to a variety of germs, bacteria and viruses, which their immune systems must battle and then remember in order for them to stay healthy. It’s the heroic nature of their immune systems, needed for survival that makes them ideal donors for transfer factors. Because transfer factors can be shared safely and effectively from human to human, chicken to human or cow to human, either source alone offers excellent immune support. Combined, they offer the broadest and deepest range of immune support available.
The following points illustrate the quality that goes into the sourcing of our transfer factors.
All of the dairy herds that produce colostrum for processing are from USDA Grade A dairy farms. As such the farm and milk must meet the standards of state and federal milk quality ordinances, including the Pasteurized Milk Ordinance (PMO). These state and federally inspected farms produce milk for the Grade A Fluid Milk Market. Milk from these farms is sold in the marketplace.
It is unlawful to use antibiotics in lactating dairy cattle that will give rise to measureable levels of antimicrobial drugs. All tanker truckloads of milk are tested in all processing plants for such residues. Contaminated milk cannot be used for fluid or processing milk purposes. The financial penalties are severe and dairy producers have redundant management schemes in place to assure that residues do not occur. USDA and FDA statutes prohibit use of antibiotics as a feed supplement in lactating dairy cattle.
Our inquiry revealed that the dairy farms that produce raw colostrum for processing do not use hormones intended to increase milk production, including rBST.
All colostrum is pasteurized in a proprietary process to assure its microbial safety and quality. Moreover, the ultra-filtration process will remove all known microorganisms. Once dried the powder is tested for viable microbes.
The agent associated with «Mad Cow Disease» (Bovine Spongiform Encephalopathy, (BSE)) has NOT been identified in the United States dairy herd. Additionally, there is no evidence of milk borne transmission in the English experience with BSE and the 36 Crutzfeldt-Jakobs Disease (CJD) patients.
All other ingredients in the Transfer Factor™ product line are «Food Grade» as defined by the US FDA Center for Food Safety and Applied Nutrition and meet the US FDA GRAS (Generally Regarded As Safe) definition.
Quality Control Protocol: Herd Management, 4Life’s™; management. «It is of utmost importance to the management of 4Life™; that we follow the most stringent quality control protocol in the care of the herds used to gather transfer factor and in the manufacturing process. The 4Life™; manufacturing facility is pharmaceutical grade. David Lisonbee has been involved to some degree or another in quality manufacturing for more than two decades. In order to accomplish this protocol, we have contracted one of the foremost authorities in this area, Richard Bennett, Ph.D.
Dr. Bennett has been an advisor to the FDA and to the USDA. He is the University of California Environmental Science Advisor in the North San Francisco Bay Region of California. He received his doctorate in Comparative Pathology at the world renowned UC Davis School of Veterinary Medicine. He has been a consultant to the National Research Council, the UC Davis Agricultural Issues Center, and to numerous national and local corporations.
Our protocol for the herds is that the farmers do not give their cows any substances (including growth hormones), which have been known to be harmful to human beings. Cows live mainly outside, where they eat off the ground, drink from shared water sources, endure varying weather conditions and contend with the challenges of communal living. This leaves them exposed to a variety of germs, bacteria and viruses, which their immune systems must battle and then remember in order for them to stay healthy. It’s the heroic nature of their immune systems, needed for survival that makes them ideal donors for transfer factors.
The herds are not placed near fields where pesticides or herbicides are used. Although it would be virtually impossible for any substance to make it through our stringent extraction and manufacturing process, this policy has been developed to address any concerns that our customers may have. There can be no antibiotics in the colostrum. If a cow is sick and has to have antibiotics, the cow is removed from the line until no antibiotics are found in its system. Any cow that shows any signs of illness is thoroughly checked out to eliminate any chance of mad cow disease or other serious conditions. Every batch is tested for contamination.
While no antibiotics can be present in the cow’s colostrum, it is advantageous to the consumer of transfer factors that a cow, at some time in its life, has consumed antibiotics. Some of the greatest threats to the human race are the antibiotic-resistant strains of bacteria, which are now killing thousands of Americans. If the cow has been administered antibiotics and has come into contact with such pathogens, then the transfer factor could possibly communicate the memory of these mutated germs to our transfer factor. Remember, the purpose of transfer factor is to communicate immunity against pathogens the cow has been in contact with. This could be of major value to the consumer because transfer factors can be shared safely and effectively from human to human, chicken to human or cow to human, either source alone offers excellent immune support. Combined, they offer the broadest and deepest range of immune support available. The herds are scattered throughout the country so that we can gather transfer factor that has been exposed to a great variety of germs. Our quality control management keeps very close supervision over the herds.
Another concern in the general public is mad cow disease. 4Life™; has a very specific strategy to avoid mad cow disease. The key to avoiding mad cow disease or any other disease is to monitor the cows very carefully, avoid practices that expose the cows to the disease, and to test every batch of product as it is being processed. Our farmers are only from the United States. The cows are not, and never have been, fed any meat-containing products. One of our tests is performed on live mice. It would be very difficult for anything like mad cow disease to slip through our safety net. The supplement industry has much more stringent controls in place than does the food industry. Regularly E. coli and salmonella slip into our nation’s food supply. The real danger is with the food industry, not the nutrition industry, especially with a top-of-the-line manufacturer such as 4Life Research™;.
Although 4Life™; is committed to being vigilant, there is evidence that BSE is not transmitted through milk type products. At a World Health Organization (WHO) Consultation organized in Geneva on April 2-3, 1996, a group of international experts reviewed the public health issues related to bovine spongiform encephalopathy (BSE) and the emergence of a new variant of Creutzfeldt-Jakob Disease (V-CJD). These scientists made the following statement: «Tests on milk from BSE-infected animals have not shown any BSE infectivity, and there is evidence from other animal and human spongiform encephalopathies to suggest that milk will not transmit these diseases. Milk and milk products, even in countries with high incidence of BSE, are therefore considered safe.»
(BSE — Mad Cow Disease), Relieving Concerns about the «Mad Cow Disease» By Richard H. Bennett, Ph.D. Expert in Infectious Disease Microbiology. All 4Life Transfer Factor products are obtained from licensed Grade A dairies that are registered with and monitored by the United States Department of Agriculture (USDA). Most importantly, science has demonstrated that mad cow disease is not transferred through milk or milk products. Dr. William Hennen, Chief Scientific Officer of 4Life Research states, “We take great care to provide products that are safe and beneficial to our friends, customers and families. BSE or mad cow disease has been known for more than ten years and we have evaluated all potential risk factors thoroughly. There is no scientific evidence that milk or colostrum pose any risk for BSE transmission.”
Over the last year, medical professionals and customers alike have raised questions about the safety of Transfer Factor™ products. Many of the questions are about TSE’s. This concern arises from the events that have taken place in England over the last 14 years.
In 1986 over 160,000 cases of bovine neurological disease were confirmed in sick cattle. The disease is called Bovine Spongiform Encephalopathy or BSE. The common linkage of this disease outbreak was the practice of feeding rendered animal waste products back to beef cattle. The infective agent is likely a Prion or a viral-like particle. The agents that cause TSE’s have not been fully identified. Just the same the BSE agents withstand heat processing of normal cooking and pasteurization. Once ingested they have the ability to infect cells, especially neurological tissues, and reproduce themselves.
The BSE agent is highly species specific as it infects the bovine almost exclusively. The concern about BSE and human health arose from a statistical linkage that suggested that a variant of the BSE agent was able to cause the human equivalent of BSE called Creutzfeldt-Jakob Disease or CJD. CJD has a genetic predisposition component and occurs worldwide at a rate of 1 per million persons. CJD has been linked to the use of Human Growth Hormone (HGH) use and transplantation of neurological tissue.
In England a variant form of CJD was identified in 14 patients as of 1996. In contrast to typical CJD, this variant affected young patients. Rigorous scientific review concluded that no definite link between BSE and the CDJ variant could be established. Circumstantial evidence suggested that consumption of meat containing the BSE agent was the likely cause. Thousands of English and European consumers were likely exposed, yet only 14 human cases have been confirmed. Milk and dairy products did not appear to be a linkage to the disease and are considered safe by UK authorities.
There are TSE’s in other animals in the US, including cats, mink, deer, elk, sheep and goats. There is no evidence of horizontal transmission to humans from these species.
In August of 1997 the FDA instituted regulations that prohibit the refeeding of most animal proteins to cattle and other ruminants. Feeding animal protein to milk cows has never been recommended and has not been the practice of the dairy producer.
In summary, we should have great confidence that all colostrum and bovine sources of thymus protein are not contaminated with the BSE agent. The programs and regulations currently in place will work effectively to ensure product safety for 4Life™ products derived from animal sources.
Sources: WHO Fact Sheet No. 133, Bovine Spongiform Encephalopathy www.who.int/inf-fs/en/fact113.html USDA, APHIS, Bovine Spongiform Encephalopathy www.aphis.usda.gov/oa/bse
Is Transfer Factor™ FDA approved? Foods and dietary supplements are not approved per se by the FDA and food supplements derived from milk would certainly fall under the category of Generally Recognized As Safe [GRAS].
Is Transfer Factor approved by the USDA? Transfer Factor XF™ is produced within the bounds of a USDA certified plant which follows established protocol for dairy production, including pasteurization and safety guidelines. Furthermore, Transfer Factor™, as a human-grade product, exceeds standards established for animal-grade products. Each batch of Transfer Factor XF™ undergoes strict microbial and potency tests to assure quality time after time.
Can it be taken with any other vitamins, ginseng or any other nutritional product? (back) Transfer Factor and Transfer Factor Plus are compatible with any other type of nutrient.
Can anyone take Transfer Factor?
People of all ages can use Transfer Factor. Transfer factor was, in fact, designed by nature for newborns. People wishing to give transfer factor to infants and children under age 12 should work closely with a medical professional on deciding what dose to take. Typically, children do well with doses half that of the adult/label dose. Infants would require somewhat less. While there is no known toxicity to transfer factor, picking doses for younger children and infants should be done with prudence.
Is Transfer Factor™ safe? Researchers have given huge doses of Transfer Factor™ to volunteers in an attempt to trigger some sort of adverse reaction. No negative side effects were observed even with massive doses.
I have heard reports of people exceeding the recommended serving size of Transfer Factor. Is this safe? Transfer Factor has been consumed for many years with no reported side effects. Studies have shown no toxicity. The recommended maintenance amount is 3 capsules a day.
Is it safe to take multiple capsules of Transfer Factor™ a day? There is no known toxicity level associated with Transfer Factor™.
Can a person use more than the recommended serving size of Transfer Factor Plus™? Some individuals do use more for added immune support during short duration. The best and safest way to begin using Transfer Factor Plus™ is to use the recommended serving size as listed on the product label.
Is there a toxic level of Transfer Factors? 4Life Transfer Factor™ has a long history of safety with millions of doses taken without incident among humans or animals. The study that Dr. See performed in vitro (on cultured blood), showed no toxicity on the blood markers when Transfer Factor was added at the amount of 2,000 times the recommended dosage.
We have had most of our office and many others on Transfer Factor for three years now with no negative affects.
As far as the biochemistry involved, there is no problem. Molecularly the structure is exactly the same as what is in our blood. The only difference is that the 8 amino acids rearrange themselves to recognize the antigens each particular transfer factor has been exposed to.
Any fear of overdose? We have tested for overdose in vitro up to 2,000 times the recommended dosage with no negative side effects.
Do Health Professionals work with Transfer Factor? Yes. There are already Health Professionals working with Transfer Factor all around the world, including many renowned surgeons and doctors who recommend Transfer Factor to all their patients.
Does any of the 4Life TF products contain IGF-1? «Insulin-like growth factor-I (IGF-I) is a growth hormone with characteristics similar to that of both insulin and growth hormone. It functions to stimulate cellular growth in a number of tissues throughout the body. IGF-I is found in human and cow colostrum and milk. Its concentration in colostrum is several hundred fold higher than in milk. In newborns, one of the major functions of IGF-I is to stimulate the growth of the gut, greatly improving its barrier functions. IGF-I can also stimulate the growth of unwanted cells, such as cancer cells. IGF-I is a large molecule. In colostrum, IGF-I is almost entirely protein bound, making it a VERY large molecule. The patented microfiltration process used by 4Life to extract Transfer Factors from colostrum will not allow compounds of this size to pass through the microfiltration membranes. In addition, current research has not conclusively shown that ingesting colostrum will increase serum IGF-I levels in humans. In fact, this research suggests that almost all of the ingested IGF-I is degraded in the stomach. While absorption does occur to a small extent in newborns, it is uncertain if any oral IGF-I is absorbed in adults. Considering these facts, we are confident that the powerful immune support offered by 4Life Transfer Factor products is due to the transfer factors themselves and not other «tag-along» molecules. Furthermore, those with cancer need not worry about undesired stimulation of cancer cell growth when taking 4Life Transfer Factor products. To the contrary, many people have reported that 4Life Transfer Factor products have been great help to them in supporting their immune systems as they have struggled with cancer.» 4Life product support Tue, 07 Dec 2004
What is the difference between Transfer Factors and colostrum? Transfer factors are the most powerful part of colostrum. Colostrum contains bovine specific antibodies that can cause allergic reactions. However, transfer factors are not species-specific and can be given to another mammal without reaction. In addition, transfer factor supplements are vastly more concentrated than colostrum alone. In fact, you would have to consume many quarts of colostrum to receive the same benefits of one transfer factor capsule.
Who makes Transfer Factor? Through a special patented process licensed to 4Life Research™ www.4-life.com, transfer factors are extracted from cow colostrum. 4Life’s™ Transfer Factor™ naturally supports the body’s immune system, communicating immune information more efficiently among the cells in the body, and ultimately enhancing the body’s ability to withstand attacks on its health. In addition, transfer factors are unique because they also contain a suppressor factor, which helps to normalize and balance an overactive immune system.
Is there a limit to how hot the product can get? Yes. Colostrum undergoes a brief heat process that is limited to proper pasteurization methods. This amount of heat does not affect transfer factor activity.
Is the Transfer Factor molecule heat sensitive? What about increased temperatures in shipping of the product to the customer? A proprietary protein stabilization method is used to maintain transfer factor activity during the processing of Transfer Factor.
But what about antibiotics? Around the same time as Dr. Lawrence’s discovery, the «miracle cure» of antibiotics came into widespread use and transfer factor research was pushed aside by many scientists and physicians. But even in the midst of the antibiotic age, dedicated clinicians persisted, spending an estimated $40 million on transfer factor research and showing clinical success throughout the world.